Ephemerisle 2017: The Bitcoin Community's Favorite ...

MAPS Completes $4 Million Matching Grant from Pineapple Fund

MAPS Completes $4 Million Matching Grant from Pineapple Fund Today, the non-profit Multidisciplinary Association for Psychedelic Studies (MAPS) announced the successful completion of the $4 million matching grant from the Pineapple Fund for U.S. Food and Drug Administration (FDA) Phase 3 clinical trials of MDMA-assisted psychotherapy for posttraumatic stress disorder (PTSD).
On January 10, 2018, the Pineapple Fund, created by an anonymous cryptocurrency philanthropist known only as "Pine," announced that they would match the next $4 million in donations to support MAPS' upcoming Phase 3 trials, with a deadline of March 10. The announcement inspired $4 million in new gifts from over 550 individuals, which the Pineapple Fund has matched in Bitcoin, for a total of $8 million. 149 of these new gifts, totaling $1,093,330, were received in cryptocurrency.
With these gifts, MAPS has now raised $26.2 million of the $26.7 million needed for its upcoming FDA Phase 3 clinical trials of MDMA-assisted psychotherapy for PTSD. MAPS now needs only an additional $500,000 to complete funding for the final stage of research needed to make MDMA-assisted psychotherapy a legal prescription treatment for PTSD in the U.S. MAPS is currently seeking an additional $5 million for European Medicines Agency (EMA) trials to supplement the data gathered for the FDA.
"Pine's extraordinary generosity has inspired many others to rise to the challenge of his $4 million matching grant," said Rick Doblin, Ph.D., MAPS' founder and executive director. "We can now truly say that MDMA-assisted psychotherapy will be a gift to the world from the psychedelic and cryptocurrency communities, with MAPS having been unable to obtain any government funding for our research."
On behalf of the millions of people and families who will benefit from legal MDMA-assisted psychotherapy for PTSD when it's approved, MAPS expresses its sincere gratitude to all of the individuals and foundations who contributed to the Pineapple Fund matching grant. Leading contributors to the match included George Sarlo ($1,000,001), James Evans ($1,000,000), Libra Foundation ($600,000), anonymous ($400,000), William H Donner Foundation ($250,000), Jason Dorsett ($200,000), Christian Halper ($200,000), Bo Shao and Oleg Gorelik ($148,235), Cyan Bannister ($50,000), George Goldsmith and Katya Malievskaia ($25,000), James Bailey ($10,000), Robert Bienstock ($10,000), and Fred and Katie Weber ($10,000).
On July 28, 2017, MAPS obtained an Agreement Letter from the FDA regarding our Phase 3 protocol design, successfully concluding FDA's Special Protocol Assessment (SPA) process. On August 15, 2017, based on the results of MAPS' Phase 2 trials, the FDA granted Breakthrough Therapy Designation to MDMA-assisted psychotherapy for PTSD, acknowledging that it "may demonstrate substantial improvement over existing therapies" and agreeing to expedite its development and review.
On March 1, 2018, MAPS had its first meeting with the European Medicines Agency (EMA) to plan the Phase 3 research that will be required to obtain approval for MDMA-assisted psychotherapy for PTSD in Europe.
Phase 3 clinical trials of MDMA-assisted psychotherapy for PTSD will begin in the summer of 2018, and will enroll 200-300 participants across 16 sites in the U.S., Canada, and Israel. Provided the Phase 3 trials demonstrate statistically significant efficacy and an acceptable safety profile, FDA approval is expected by 2021.
In MAPS' completed Phase 2 trials with 107 participants, 68% no longer qualified for a diagnosis of PTSD twelve months following treatment. These participants all had chronic, treatment-resistant PTSD, and only required three sessions of MDMA-assisted psychotherapy, along with twelve 90-minute psychotherapy sessions for preparation and integration.
Every year in the U.S., 8 million people are suffering from PTSD, with an estimated 300 million PTSD sufferers worldwide. With approximately 27% of suicides in the U.S. associated with PTSD, and an average of 20 veterans committing suicide every day, there is an urgent need for more effective treatments for PTSD.
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Released List of Satoshi Roundtable Attendees Gathering this Weekend

Satoshi Roundtable II
This weekend a group of blockchain and bitcoin industry leaders gather again for the Satoshi Roundtable (satoshiroundtable.org) retreat. Participants in the second Satoshi Roundtable include developers, CEOs, investors, adopters and influencers from the blockchain and bitcoin world.
The retreat is limited to approximately 75 attendees and designed to encourage organic, participant-driven discussion free of the distractions of a conference.
Sessions include several topics of overall blockchain interest and a roundtable discussion on bitcoin capacity.
Please provide any suggestions you have for areas of discussion/ focus.
Partial list of confirmed participants:
Gabriel Abed, CEO, Bitt Charles Allen, CEO, BTCS Gavin Andresen, MIT / Bitcoin Foundation Adam Back, President, Blockstream David Bailey, CEO, yBitcoins Mike Belshe, CEO, BitGo Patrick Byrne, CEO, Overstock / T0 Michael Cao, CEO, zoomhash Dave Carlson, CEO, Mega Big Power Daniel Castagnoli, CCO Exodus Sam Cole, CEO, KNC Miner Matt Corallo, Core Developer Luke Dashjr, Core Developer Anthony Di Iorio, CDO-Toronto Stock Exchange, Founder-Ethereum/Decentral/Kryptokit Joe Disorbo, CEO, Webgistix Jason Dorsett, Early Adopter Evan Duffield, FoundeLead Scientist, Dash Andrew “Flip” Filipowski, Partne Co-Founder, Tally Capital Thomas France, Founder, Ledger Jeff Garzik, Founder, Bloq Yifo Guo, Tech Develope Early Adopter David Johnston, Chairman, Factom Samy Kamkar, Super Hacker Alyse Killeen, Partner, Venture Capital Investor Jason King, Founder, Unsung Mike Komaransky, Cumberland Mining Peter Kroll, Founder, bitaddress.org Bobby Lee, CEO, BTC China, Vice-Chairman of the Board, Bitcoin Foundation Charlie Lee, Director of Engineering, Coinbase/Founder of Litecoin Eric Lombrozo, Founder, Ciphrex Corp / Developer Marshall Long, CTO, Final Hash Matt Luongo, CEO, Fold Jake Mazulewicz, Ph.D. JMA Associates (guest speaker) Human performance researcher Halsey Minor, CEO, Uphold / Founder of CNet Alex Morcos, Hudson Trading/ Core Developer Neha Narula, MIT, Director of DCI – Digital Currency Initiative Dawn Newton, Co-Founder, COO, Netki Justin Newton, Founder CEO, Netki Stephen Pair, Co-FoundeCEO, BitPay Inc. Michael Perklin, President, C4 – CryptoCurrency Certification Consortium / Board Member, Bitcoin Foundation Alex Petrov, CIO, BitFury Phil Potter, CFA, Bitfinex Francis Pouliot, Director, Bitcoin Embassy, Board Member, Bitcoin Foundation JP Richardson, Chief Technical Officer, Exodus Jamie Robinson, QuickBt Jez San, Angel Investor Marco Santori, Partner, Pillsbury Scott Scalf, EVP/Head of Tech Team, Alpha Point Craig Sellars, CTO, Tether Ryan Shea, Co-Founder, One Name Greg Simon, CEO & Co-Founder Ribbit! Me / President, Bitcoin Association Paul Snow, CEO Factom, Texas Bitcoin Conference Riccardo Spagni, Monero Nick Spanos, Founder, Bitcoin Center NYC Elizabeth Stark, Co-Founder & CEO, Lightning Marco Streng, CEO, Genesis Mining Nick Sullivan, CEO, ChangeTip Paul Sztorc, Truthcoin Michael Terpin, CEO, Transform Group Peter Todd, Core Developer Joseph Vaughn Perling, New Liberty Dollar Roger Ver, CEO, Memory Dealers / Bitcoin.com Aaron Voisine, CEO, Breadwallet Zooko Wilcox, CEO, Z Cash Shawn Wilkinson, Founder, Storj Micah Winkelspecht, CEO, Gem
Also, representatives from Blockchain, Bain Capital Ventures, Mycelium, Fidelity Investments and others.
submitted by bruce_fenton to Bitcoin [link] [comments]

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